Hierarchy of supraventricular pacemakers

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Hierarchy of ventricular pacemakers.

To characterize the pattern of pacemaker dominance in the ventricular specialized conduction system (VSCS), escape ventricular pacemakers were localized and quantified in vivo and in virto, in normal hearts and in hearts 24 hours after myocardial infarction. Excape pacemaker foci were localized in vivo during vagally induced atrial arrest by means of electrograms recorded from the His bundle an...

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Depression of escape pacemakers associated with rapid supraventricular rate in patients with atrioventricular block.

Intermittent failure of escape pacemakers to maintain an effective rate when the supraventricular rate was rapid was observed in three patients with complete, or high degree atrioventricular block. In two of these patients asystole or slowing of escape pacemaker rate to less than 20 per minute was reproduced by atrial pacing at rates from 125 to 150 per minute. We localized the site of the bloc...

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Biological Pacemakers

Genetically engineered pacemakers could be a possible alternative to implantable electronic devices for the treatment of bradyarrhythmias. The strategies include upregulation of beta adrenergic receptors, conversion of myocytes into pacemaker cells and stem cell therapy. Pacemaker activity in adult ventricular myocytes is normally repressed by the inward rectifier potassium current (I(K1)). The...

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Mechanism of supraventricular parasystole.

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ژورنال

عنوان ژورنال: The Journal of Thoracic and Cardiovascular Surgery

سال: 1980

ISSN: 0022-5223

DOI: 10.1016/s0022-5223(19)37721-9